Attention fans, we already have the official date of the sequel! This Friday part 2 of Season 2 of the Anime Kusuriya at The Apothecary Diaries has gained trailer and release date.
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Therefore the continuation of Kusuriya Season 2 at Hitorigoto debuts on April 4, 2025 with animation from Toho Animation Studio and Studio × Olm.

Synopsis:
Maomao, a pharmacist's daughter with an unusual fascination with poisons and medicine, and Jinshi, a handsome and enigmatic eunuch, face more complex mysteries within the imperial court! With the confirmation of the pregnancy of the emperor's favorite consort, Lady Gyokuyo, Maomao returns to the Jade Palace as his poison tester. While he was vigilant to prevent new attacks on the consort and the imperial heir from occurring, several other issues began to arise: the entry of a new consort, Lady Loulan, daughter of a powerful minister from the era of the former emperor; an unsolved case that put Jinshi's life at risk; and the unknown whereabouts of the suspect, Sui Rei. However, in the midst of this tense atmosphere, foreign traders and an emissary arrive at the palace with absurd demands.
However, Kusuriya no Hitorigoto ( Diaries of an Apothecary ) began publication in October 2011 in Shousetsuka ni Narou . Finally, the novel had two manga adaptations, the first by Nekokurage published in Big Gangan and the second in Sunday Gene-X.
Source: Official Website